Spritam (Levetiracetam) for Epilepsy

Overview
Spritam, approved by the U.S. Food and Drug Administration (FDA), is a treatment for epilepsy. It is prescribed for partial-onset seizures in individuals aged 4 years and older weighing more than 20 kilograms (around 44 pounds). It is also indicated as an adjunctive therapy (along with other medications) for treating myoclonic seizures in those aged 12 years and older with juvenile myoclonic epilepsy and primary generalized tonic-clonic seizures in people aged 6 years and older with idiopathic generalized epilepsy. Spritam is also known by its drug name, levetiracetam.

Levetiracetam is part of a group of drugs called anticonvulsants. It is thought to work by changing the way neurotransmitters (brain chemicals) are released, helping to calm overactive brain activity and lower the chance of seizures.

How do I take it?
Prescribing information states that Spritam is taken by mouth as tablets for suspension. The tablets are designed to disintegrate in the mouth when taken with a sip of liquid and should only be swallowed after disintegration. Alternatively, the tablet can be added to a small amount of liquid in a cup, allowed to disperse, and then consumed immediately. Partial tablets should not be used. The dosing schedule varies by condition and person’s weight but generally starts with a twice daily schedule that’s adjusted every two weeks. Spritam should be taken exactly as prescribed by a health care provider.

Side effects
Common side effects of Spritam include somnolence (drowsiness), asthenia (weakness), infection, dizziness, fatigue, aggression, nasal congestion, decreased appetite, and irritability.

Rare but serious side effects may include psychotic symptoms, suicidal thoughts or behaviors, serious dermatological reactions (such as rash), coordination difficulties (ataxia and incoordination), and Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS), a severe allergic reaction involving multiple organs.

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Label: Spritam — Levetiracetam Tablet, for Suspension — DailyMed