@A MyEpilepsyTeam Member , Around 2014 I found out that long term use of Depakote could possibly cause Osteoporosis & the Neurologist I had just begun seeing who told me that had me do a bone density test cause it was my Pediatric Neurologist who had started me on the Depakote several years earlier & the bone density test showed that I have Osteopenia in my left hip & so he recommended I take Vitamin D & my current Neurologist has me taking the Vitamin D also. Your friend in Texas, Becky

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A MyEpile...

Btw, I am recently reading about Neuroinflammation and Epilepsy. Do a search online. It seems that there may be a connection between inflammatory diseases and epileptic seizures.

The answers here are so long, I forgot the question. But every SSRI, SNRI, Tricyclic plus Depakote, and now Keppra caused my neuropathy to flare up out of control. All of those spiked nerve pain, electrical shock like spiking pain, burning, muscle spasm or muscle torsion that lasted for hours for each trial. Sometimes, a trial medication, I immediately reacted within 24 hours or less, some a week or month or more but within months at least. Carbamazepine caused me to have severe, more than my typical myoclonus in the daytime. My legs gave out from under me. I went to ER a few times. So, basically everything but gabapentin has caused me some painful or in the lack of tone, loss of total sensation, experience. I would say, that my everyday neuropathy was flared with all those seizure inducing reactions to medications.

Oh, I forgot. Yes on neuropathy. I have had neuropathy since I was twenty after a bone reconstruction surgery in the Army. First it was the left half of my body. I had a bone graft from my left hip to my left collarbone. So, the neuropathy was like being on fire, burning and stinging. But after some years, two or three years, my right side began to have the same sensations. That was since 1987 and thereafter. There was never a total explanation by medical doctors about why I had neuropathy. And, if I ask today, they still do not know, they say.

@A MyEpilepsyTeam Member I'm not sure whether your talking to me or not but this is what happened to me:
I had to have a 4-day video eeg test and was having very obvious shaking during the test I have done the arms forward test and finger touch test a few times and even when I feel fine and do it my arms and hands will start to shake. I can't remember but I may have even done it when I was doing the video eeg but not under instruction. When I was put on Keppra this helped a lot with the jerks and twitches, so these are cut right back now I might get one to three a week. But I still get micro shaking in my hands mainly but sometimes in my legs. In terms of tingling, I only get this in my hands and feet most of the time it's not that bad and I can get rid of it very quickly but there have been a few times where my hand or foot will basically feel like it's locked up and I have to get it moving to stop the tingling.

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