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Real members of MyEpilepsyTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Has Anyone Ever Experienced Fluid Retention While Taking Keppra?

A MyEpilepsyTeam Member asked a question 💭
Brunswick, AU

I've been taking Keppra for almost 8 years now and off and on I've experienced unsightly fluid retention in the legs and stomach. I've never thought to associate the two previously but in the warmer months it gets pretty bad.

I was just wondering if anyone else has experienced something similar while taking Keppra or perhaps I just have a predisposition to fluid retention....

If you have experienced it how have you managed it?

January 29, 2020
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View reactions
A MyEpilepsyTeam Member

My daughter has been on keppra and 2 other seizure meds and has never had that side effect! For 13 years now!

February 8, 2020
A MyEpilepsyTeam Member

Heavy sweating, nausea, vomiting, dark colored urine from dehydration.Plus you can Google Keppra.

January 29, 2020
A MyEpilepsyTeam Member

It turns out after writing it I was diagnosed with lower limb lymphoedema. I wear compression stockings every day.

I also have an unfortunate gene mutation Leiden factor 5 which means I'm 8 time more likely to develop a blood clot. The general thought of the lymphoedema clinic I see is that I most like had previously undiagnosed blood clots which led to the lymphoedema.

January 12
A MyEpilepsyTeam Member

No I can't control it. I have been on Keppra 14 years or longer

October 29, 2023
A MyEpilepsyTeam Member

My son was put on keppra and he gained 20 kilos in one year. His stomach has remained bloated even though he’s off keppra. It was devastating for him and compromised his mobility

January 31, 2023

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